After a disastrous niacin self experiment confirmed once and for all that my liver is a shadow of its former self, I experimented with a selection of OTC supplements frequently mentioned in discussion forums on liver damage. Glutathione did nothing as far as I could tell, N-acetyl cysteine (NAC) and alpha lipoic acid (ALA) do not agree with me, and I was already taking vitamin B6 in the form of P5P. Methionine was the only other supplement I could tolerate.
Within days the scariest of the liver symptoms had gone. After several weeks it became apparent that it also had a significant effect on my heavy periods. With 1500 mg of methionine, I had a manageable period, like a normal person’s — easier even than what vitamin K2 supplements did for me. Since I had recently taken truckloads of niacin, I couldn’t be sure it wasn’t the niacin that did it, so I stopped the methionine and voila, back to the old Maxi Curse.
The 1500 mg dose turned out to completely stop me sleeping, so I tried 1000 mg. Subsequent periods were indeed easier, although not as easy as on 1500 mg.
Illustration: Detail of 1940s American Airlines travel poster by E. McKnight Kauffer.